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Comparative Study of Proliferation of Bovine Albumin Serum on Different Metallic Substrates for Biomedical Applications

Received: 22 January 2023     Accepted: 13 July 2023     Published: 5 December 2023
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Abstract

Pure titanium (Ti), titanium alloys, and different types of stainless steel are often employed for applications in orthopedic implants. Among these, titanium is considered the “gold standard.” However, tissue reactions around these metal surfaces and the changing trend to leave orthopedic devices in the body have led to a new examination of the preferred material. Nowadays various metallic materials are commonly employed to improve the life time of bioimplants. Three types of metals (SS-316L, SS-304L and pure Titanium) were used for a comparative study by considering adsorption properties of all. Metallic materials are attractive due to properties like less coefficient friction, high hardness value, and chemically inert in nature which make them attractive to be used in biochemical devices. The surface of these metals was prepared to study the adhesion of different type of animal proteins adhesion on their surface. Protein growth on these materials was studied by using AFM (atomic force microscope), SEM and FTIR at different time intervals (24h, 48h, 72h, 96h). The difference in density and weight of the samples before and after the adsorption of protein on substrates confirms the proliferation process on metals. Promising results were obtained at time interval of 96 hours. Overall, all the samples show similar behavior.

Published in International Journal of Biomedical Materials Research (Volume 11, Issue 1)
DOI 10.11648/j.ijbmr.20231101.11
Page(s) 1-5
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2023. Published by Science Publishing Group

Keywords

Biocompatibility, Bovine Serum, Comparative Study, Metallic Materials

References
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Cite This Article
  • APA Style

    Nosheen, S., Habib, F., Irfan, M., Waseem, B., Iqbal, W. (2023). Comparative Study of Proliferation of Bovine Albumin Serum on Different Metallic Substrates for Biomedical Applications. International Journal of Biomedical Materials Research, 11(1), 1-5. https://doi.org/10.11648/j.ijbmr.20231101.11

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    ACS Style

    Nosheen, S.; Habib, F.; Irfan, M.; Waseem, B.; Iqbal, W. Comparative Study of Proliferation of Bovine Albumin Serum on Different Metallic Substrates for Biomedical Applications. Int. J. Biomed. Mater. Res. 2023, 11(1), 1-5. doi: 10.11648/j.ijbmr.20231101.11

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    AMA Style

    Nosheen S, Habib F, Irfan M, Waseem B, Iqbal W. Comparative Study of Proliferation of Bovine Albumin Serum on Different Metallic Substrates for Biomedical Applications. Int J Biomed Mater Res. 2023;11(1):1-5. doi: 10.11648/j.ijbmr.20231101.11

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  • @article{10.11648/j.ijbmr.20231101.11,
      author = {Sumaira Nosheen and Farzana Habib and Muhammad Irfan and Bilal Waseem and Waqas Iqbal},
      title = {Comparative Study of Proliferation of Bovine Albumin Serum on Different Metallic Substrates for Biomedical Applications},
      journal = {International Journal of Biomedical Materials Research},
      volume = {11},
      number = {1},
      pages = {1-5},
      doi = {10.11648/j.ijbmr.20231101.11},
      url = {https://doi.org/10.11648/j.ijbmr.20231101.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijbmr.20231101.11},
      abstract = {Pure titanium (Ti), titanium alloys, and different types of stainless steel are often employed for applications in orthopedic implants. Among these, titanium is considered the “gold standard.” However, tissue reactions around these metal surfaces and the changing trend to leave orthopedic devices in the body have led to a new examination of the preferred material. Nowadays various metallic materials are commonly employed to improve the life time of bioimplants. Three types of metals (SS-316L, SS-304L and pure Titanium) were used for a comparative study by considering adsorption properties of all. Metallic materials are attractive due to properties like less coefficient friction, high hardness value, and chemically inert in nature which make them attractive to be used in biochemical devices. The surface of these metals was prepared to study the adhesion of different type of animal proteins adhesion on their surface. Protein growth on these materials was studied by using AFM (atomic force microscope), SEM and FTIR at different time intervals (24h, 48h, 72h, 96h). The difference in density and weight of the samples before and after the adsorption of protein on substrates confirms the proliferation process on metals. Promising results were obtained at time interval of 96 hours. Overall, all the samples show similar behavior.
    },
     year = {2023}
    }
    

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    T1  - Comparative Study of Proliferation of Bovine Albumin Serum on Different Metallic Substrates for Biomedical Applications
    AU  - Sumaira Nosheen
    AU  - Farzana Habib
    AU  - Muhammad Irfan
    AU  - Bilal Waseem
    AU  - Waqas Iqbal
    Y1  - 2023/12/05
    PY  - 2023
    N1  - https://doi.org/10.11648/j.ijbmr.20231101.11
    DO  - 10.11648/j.ijbmr.20231101.11
    T2  - International Journal of Biomedical Materials Research
    JF  - International Journal of Biomedical Materials Research
    JO  - International Journal of Biomedical Materials Research
    SP  - 1
    EP  - 5
    PB  - Science Publishing Group
    SN  - 2330-7579
    UR  - https://doi.org/10.11648/j.ijbmr.20231101.11
    AB  - Pure titanium (Ti), titanium alloys, and different types of stainless steel are often employed for applications in orthopedic implants. Among these, titanium is considered the “gold standard.” However, tissue reactions around these metal surfaces and the changing trend to leave orthopedic devices in the body have led to a new examination of the preferred material. Nowadays various metallic materials are commonly employed to improve the life time of bioimplants. Three types of metals (SS-316L, SS-304L and pure Titanium) were used for a comparative study by considering adsorption properties of all. Metallic materials are attractive due to properties like less coefficient friction, high hardness value, and chemically inert in nature which make them attractive to be used in biochemical devices. The surface of these metals was prepared to study the adhesion of different type of animal proteins adhesion on their surface. Protein growth on these materials was studied by using AFM (atomic force microscope), SEM and FTIR at different time intervals (24h, 48h, 72h, 96h). The difference in density and weight of the samples before and after the adsorption of protein on substrates confirms the proliferation process on metals. Promising results were obtained at time interval of 96 hours. Overall, all the samples show similar behavior.
    
    VL  - 11
    IS  - 1
    ER  - 

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Author Information
  • PCSIR Laboratories Complex, Lahore, Pakistan

  • PCSIR Laboratories Complex, Lahore, Pakistan

  • PCSIR Laboratories Complex, Lahore, Pakistan

  • PCSIR Laboratories Complex, Lahore, Pakistan

  • PCSIR Laboratories Complex, Lahore, Pakistan

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