Research Article
Comparative Study of Proliferation of Bovine Albumin Serum on Different Metallic Substrates for Biomedical Applications
Sumaira Nosheen*,
Farzana Habib,
Muhammad Irfan,
Bilal Waseem,
Waqas Iqbal
Issue:
Volume 11, Issue 1, December 2023
Pages:
1-5
Received:
22 January 2023
Accepted:
13 July 2023
Published:
5 December 2023
Abstract: Pure titanium (Ti), titanium alloys, and different types of stainless steel are often employed for applications in orthopedic implants. Among these, titanium is considered the “gold standard.” However, tissue reactions around these metal surfaces and the changing trend to leave orthopedic devices in the body have led to a new examination of the preferred material. Nowadays various metallic materials are commonly employed to improve the life time of bioimplants. Three types of metals (SS-316L, SS-304L and pure Titanium) were used for a comparative study by considering adsorption properties of all. Metallic materials are attractive due to properties like less coefficient friction, high hardness value, and chemically inert in nature which make them attractive to be used in biochemical devices. The surface of these metals was prepared to study the adhesion of different type of animal proteins adhesion on their surface. Protein growth on these materials was studied by using AFM (atomic force microscope), SEM and FTIR at different time intervals (24h, 48h, 72h, 96h). The difference in density and weight of the samples before and after the adsorption of protein on substrates confirms the proliferation process on metals. Promising results were obtained at time interval of 96 hours. Overall, all the samples show similar behavior.
Abstract: Pure titanium (Ti), titanium alloys, and different types of stainless steel are often employed for applications in orthopedic implants. Among these, titanium is considered the “gold standard.” However, tissue reactions around these metal surfaces and the changing trend to leave orthopedic devices in the body have led to a new examination of the pre...
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